Ctt meta-analysis
WebJan 12, 2008 · We undertook a prospective meta-analysis to help resolve these uncertainties. Methods: Findings: During a mean follow-up of 4.3 years, there were 3247 major vascular events in people with diabetes. There was a 9% proportional reduction in all-cause mortality per mmol/L reduction in LDL cholesterol in participants with diabetes … WebApr 10, 2024 · We conducted a meta-analysis on 19 of the 21 trials that reported data on all-cause mortality and 18 trials reporting data on MI and stroke. The ARR was 0.8% for all-cause mortality, 1.3% for MI, and 0.4% for stroke. ... another CTT analysis reported that the risk treating 10000 patients with statins for 5 years could result in 5 cases of ...
Ctt meta-analysis
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WebThe summary of the 2012 Cholesterol Treatment Trialists (CTT) meta-analysis is unique because it shows trial results according to baseline risk.3 For nonfatal stroke and … WebMay 18, 2016 · The landmark Cholesterol Treatment Trialists' (CTT) meta-analysis projected a 21% reduction in major vascular events per 1 mmol/L reduction in LDL-C with statins over a median of approximately 5 years of follow up. 13 In the aforementioned trials, 2,3 PCSK9 inhibitors achieved an LDL-C reduction of 1.83 mmol/L and 1.89 mmol/L for …
WebAug 29, 2024 · The researchers compiled data from 23 trials from the Cholesterol Treatment Trialists’ (CTT) Collaboration, with information on nearly 155,000 patients. All … WebFeb 12, 2024 · Instead, the change in the 2013 Cochrane review was based largely on a meta-analysis by the Cholesterol Treatment Trialists’ (CTT) Collaboration, published in 2012 According to the Cochrane review, the 2012 CTT Collaboration further demonstrated a consistent 20% relative risk reduction in major vascular events with statins per 1mmol/L ...
WebEVIDENCE OF BENEFIT. The CTT Collaboration meta-analysis used individual patient data from 22 randomised controlled trials (RCTs) of statin versus control (n = 134 537); 3 authors were able to stratify individuals into risk categories.The CTT Collaboration is the only group to have been granted access to individual patient data by pharmaceutical … WebNov 13, 2010 · Background: Lowering of LDL cholesterol with standard statin regimens reduces the risk of occlusive vascular events in a wide range of individuals. We aimed to assess the safety and efficacy of more intensive lowering of LDL cholesterol with statin therapy. Methods: We undertook meta-analyses of individual participant data from …
WebJan 8, 2015 · We did a meta-analysis of studies included in the CTT Collaboration database reported up to 2010; the database includes trials of statin therapy versus control and trials that compared statin regimens of …
WebAug 25, 2024 · CTT meta-analysis of the effects of statins on muscle symptoms. C Baigent. Monday, August 29, 2024; 2:00 PM–3:15 PM Meet the Experts. Meet the Experts: Atherosclerosis Regression and Plaque Modification. Potent LDL lowering and plaque modification in patients with coronary atherosclerosis. fishy phonicsWeb• Psychometrics (CTT and IRT) • Factor Analysis • Meta-Analysis • ANOVA / Regression / Correlation / Predictive Modeling • Data … candy \u0026 schonwaldWebAug 29, 2024 · An analysis of data from 23 trials within the Cholesterol Treatment Trialists’ (CTT) Collaboration, results of the study suggest the excess risk for muscle symptoms … candy\u0027s alterations yakimaWebApr 11, 2015 · We undertook a meta-analysis of statin trials in the Cholesterol Treatment Trialists' (CTT) Collaboration database to compare the effects of statin therapy between women and men. Interpretation: In men and women at an equivalent risk of cardiovascular disease, statin therapy is of similar effectiveness for the prevention of major vascular … fishy personWebThe Cholesterol Treatment Trialists’ (CTT) Collaboration was established in 1994 after it was recognised that no single randomised controlled trial of a lipid intervention would … candy \u0026 the kissesWebJun 4, 2012 · The CTT meta-analysis has many strengths but also a number of limitations, which have not been discussed and which, given the clinical implications, require … The concern for statin-induced hepatotoxicity leads to the underuse of … Review of current evidence and clinical recommendations on the effects of low … candy \u0026 cigarettes wikiWebThese findings suggest that the CTT meta-analysis of statin trials finding that each 39-mg/dL (1-mmol/L) reduction in LDL-C level was associated with a hazard ratio of 0.78 … candy \\u0026 schonwald