Phospho-sting-s366

Author: sjfx

August undefined, 2024

Phospho-STING (Ser366) (D7C3S) Rabbit mAb recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. Background WebPhospho Sting S366, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 2 PubMed citations. ZERO BIAS - scores, article …

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WebHTRF phospho-STING (S366) 64STGPEG HTRF total-STING 64NTGPEG HTRF phospho-TBK1 (S172) 64TBKPEG HTRF total-TBK1 64NTBPEG HTRF phospho-IRF3 (S386) 6FRF3PEG HTRF human IFNb 62HIFNBPEG Compounds References 2’3’ cGAMP C161-Biolog c-diAMP C088-Biolog c-diGMP C057-Biolog DMXAA D5817 –Sigma-Aldrich. WebPhospho-TMEM173/STING (Ser366) Antibody Phospho-TMEM173/STING (Ser366) Antibody - #AF7416 (6) (9) WB IHC IF/ICC pElisa Cites 1 /9 Western blot analysis of extracts from UV treated RAW264. View similar products>> Related products Secondary Antibodies Loading Controls Blocking Peptides Cat.#S0018 Cat.#S0006 Cat.#S0008 Cat.#S0001 Cat.#S0013 … imdb willow tv

Phospho-STING (Ser366) (E9A9K) Rabbit mAb 50907S from Cell …

WebPhosphorylated S366 is a docking site for IRF3 and is essential for the subsequent induction of Interferons (IFNs) ( 7, 8 ). Our previous work demonstrated that IRF3 binds to phosphorylated STING in the late endosomal compartment, where TBK1 phosphorylates and activates IRF3 ( 9 ). Additional proteins regulate the trafficking of STING. WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top … Web55. A method of treating, inhibiting, reducing, ameliorating, and/or preventing a cancer and or metastasis in a subject comprising administering to a subject an adoptive immunothe imdb willow hubert

Phospho-STING (Ser366) (D7C3S) Rabbit mAb 19781S from Cell …

STING Pathway Expression Identifies NSCLC With an Immune …

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. Storage: … WebProduct Description. This Cell Signaling Technology antibody is conjugated to Alexa Fluor ® 488 fluorescent dye and tested in-house for direct flow cytometric and immunofluorescent analysis in human cells. The antibody is expected to exhibit the same species cross-reactivity as the unconjugated Phospho-STING (Ser366) (D8K6H) Rabbit mAb #40818. imdb windows 10 appWebWestern blot - Phospho-STING/TMEM173-S366 Rabbit pAb (AP1223) Western blot analysis of THP-1, using Phospho-STING/TMEM173-S366 … imdb winds of war

"WebOct 24, 2013 · We conclude that phosphorylation of S366 (S365 in murine STING) occurs after autophagy and may negatively regulate STING activity to prevent sustained type I IFN production following activation by cytosolic dsDNA. Download : Download high-res image (515KB) Download : Download full-size image Figure S2. " - Phospho-sting-s366

Phospho-sting-s366

STING HTRF offer to bridge innate and adaptive immunity

WebSTING (human) S366-p. 19781 : Phospho-STING (Ser366) (D7C3S) Rabbit mAb WebApr 6, 2024 · Binding of TBK1 to this motif promotes the phosphorylation of S366 in the STING tail 19, which subsequently recruits and promotes the phosphorylation of the transcription factor interferon...

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Web靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF … WebApr 6, 2024 · STING is a transmembrane dimeric protein that is located in the endoplasmic reticulum or in the Golgi apparatus. ... Binding of TBK1 to this motif promotes the …

WebPhospho-STING (Ser366) (E9A9K) Rabbit mAb from Cell Signaling Technology Supplier PageView Company Product Page Product Specs Company Info Reviews Back To Top Biocompare is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. About Biocompare About Biocompare

WebThe work by Lehmann et al classified TNBC into six subtypes in 2011. 5 Following this, two studies at our center further identified four transcriptome-based subtypes in TNBC: luminal androgen receptor (LAR), immunomodulatory (IM), basal-like immune-suppressed (BLIS), and mesenchymal-like (MES). 6 7 Furthermore, several reports have also … WebOct 19, 2024 · Here, we looked for a mechanism that explains how STING-dependent immune signalling is ended. We tracked activated STING (phosphorylated at S366; hereafter pSTING)) (ref. 17) along its intracellular trafficking route by high-resolution confocal and Airyscan microscopy in HeLa cells.

WebSep 23, 2024 · These findings provide insight into the mechanisms of PARPis in CAR-T cell therapy for RCC and suggest a promising adjuvant therapeutic strategy for CAR-T cell therapy in solid tumors. Supplementary Information The online version contains supplementary material available at 10.1186/s13045-021-01168-1.

WebFeb 7, 2024 · TBK-independent phosphorylation of STING(S366) and its adaptor molecule TICAM2 by phospho-AKT(T308S473) augmented downstream IRF3-dependent IDO1 transcription, which was also dependent on β-catenin. imdb willow movieWebPhospho-STING (Ser366) two-plate assay protocol. The two-plate protocol involves culturing cells in a 96-well plate before lysis then transferring lysates to a low volume detection plate (either HTRF 384-lv or 96-lv plate) before adding HTRF Phospho-STING (Ser366) detection reagents. This protocol enables the cells' viability and confluence to ... imdb willow wilson home improvementWebAnti-Phospho-STING-S365 antibody produced in rabbit; find Sigma-Aldrich-SAB5701942 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Anti-Phospho-TMEM173-S366 antibody produced in rabbit. View Price and Availability. ... Anti-phospho-Smad2/3 (pThr 8) antibody produced in rabbit. affinity ... imdb windfall castWebMay 1, 2024 · (A) Heatmap shows correlation of phospho-STING (Ser_366) protein levels with cGAS and other immune-related proteins in the MD Anderson PROSPECT cohort, … list of murders in vermontWebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a ubiquitously expressed protein found predominantly in the ER (1). The enzyme cGAMP synthase (cGAS) produces the second messenger cyclic … list of muscle exercisesWebPhospho-STING (Ser366) Antibody (PA5-105674) in ICC/IF. Immunofluorescent analysis of Phospho-STING (Ser366) in HepG2 cells … imdb wings castWebOct 19, 2024 · Extended Data Fig. 9 Density maps and structural models of the AP-1–pSTING complex. The density maps (grey mesh) of AP-1 and pSTING contoured at 3σ. The protein structures fitted into the density... imdb windy city heat